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Tuesday 30 June 2009

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T05001: Synthesis of labelled and unlabelled isoflavonoid phytoestrogen standards

Wednesday 22 October 2003

This research project aims to produce analytical standards for the accurate measurement of phytoestrogens in food.

• Study Duration
• Contractor
• Background
• Research Approach

Study Duration : June 1998 to May 2002

Contractor : University of St. Andrews

Background

The ability to accurately measure phytoestrogens in food as well as in samples of blood and urine is vital to be able to assess the human exposure and biological effects of these compounds. Analysis is critically dependent on the availability of pure labelled and unlabelled analytical standards for phytoestrogens and their metabolites. However, the range and availability of these compounds is limited. This project will develop methods for the preparation of analytical standards for phytoestrogens and their metabolites.

Research Approach

Labelled ( ¹³ C labels) and unlabelled phytoestrogens and their metabolites will be prepared using synthetic chemical methods for use in analytical studies.

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