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'Extremely low' risk of GM transfer

Thursday 11 July 2002

A series of FSA research projects have concluded that it is extremely unlikely that genes from genetically modified (GM) food can end up in bacteria in the gut of people who eat them.

The Agency’s independent advisers on genetically modified foods had expressed concern about the presence of a particular gene (an antibiotic resistance marker) in GM maize approved for consumption by the European Community. This led the Agency to commission five related research projects to investigate the transfer and survival of DNA - the fundamental genetic material of all living things - in the bacteria of the human gut.

The most recently completed study - which will be published in a scientific journal later this year - shows that in real-life conditions with human volunteers, no GM material survived the passage through the entire human digestive tract. Although some DNA survived in laboratory-created environments that simulated human or animal gastrointestinal tracts, the research concluded that the likelihood of functioning DNA being taken up by bacteria in the human or animal gut is extremely low.

Much of the work from the first four research projects has already been published in respected scientific journals. All five reports, including the study involving human volunteers, can be accessed via the links below.

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Related links

FSG01007 - Survival of ingested DNA in the gut and the potential for genetic transformation of resident bacteria

Download pdf  (pdf 1MB) G010008 - Evaluating the risks associated with using GMOs in human foods (Two reports)

Download pdf  (pdf 542KB) G01010 - Assessment of risks of transferring antibiotic resistance determinants from transgenic plants to micro-organisms

Download pdf  (pdf 42KB) G01011 Dissemination of GM DNA and antibiotic resistance genes via rumen microorganisms

Download pdf  (pdf 1MB) (External) Get Adobe Acrobat reader You may need the free Acrobat Reader to view a pdf

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